Pain

Synonyms: Suffering, affliction, torment, soreness, aching, throb, smarting, sting, twinge, stab, spasm, cramp, stiffness, agony, torture, discomfort, ache, hurt, throbbing, pricking, stinging, shooting pain, pang, stitch, irritation, and tenderness.

Synonyms: Sorrow, heartache, sadness, distress, misery, despair, mental suffering, trauma, anguish, tribulation, woe, torment, grief, heartbreak, unhappiness, desolation, wretchedness, desperation, emotional suffering, bitterness, affliction, vexation, agony, and torture.

Synonyms: Nuisance, bother, irritant, worry, inconvenience, tribulation, source of aggravation, thorn in the flesh, pain in the neck, pest, vexation, source of irritation/annoyance, problem, trial, plague, bore, the bane of one's life, and drag.

Synonyms: Care, bother, labour, strain, try hard, make an effort, spare no effort, take care, apply oneself, strive, try, toil, aim, do all one can, give (it) one's all, bend/fall/lean over backwards, effort, trouble, exertion, struggle, make a great effort, make every effort, take (great) pains, put oneself out, exert oneself, endeavour, battle, work, do one's best, do one's utmost, go all out, and give it one's best shot.

Synonyms: Hurt, be painful, ache, smart, prickle, pinch, cause discomfort, kill, sadden, distress, trouble, bother, disturb, harrow, afflict, mortify, torture, gnaw at, cause pain, be sore, throb, burn, sting, twinge, be tender, play up, grieve, make miserable/wretched, worry, perturb, oppress, cause anguish to, cut to the quick, torment, and wound.